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Sensitivity % (TP/(TP+FN) Specificity %
Single nucleotide variants 99.65% (412,456/413,893) >99.99%
Insertions, deletions and indels by sequence analysis
1-10 bps 96.94% (17,070/17,608) >99.99%
11-50 bps 99.07% (957/966) >99.99%
Copy number variants (exon level dels/dups)
Clinical samples (small CNVs, n=52)
1 exon level deletion 92.3% (24/26) NA
2 exons level deletion/duplication 100.0% (11/11) NA
3-7 exons level deletion/duplication 93.3% (14/15) NA
Microdeletion/-duplication sdrs (large CNVs, n=37))
Size range (0.1-47 Mb) 100% (37/37)
Simulated CNV detection
2 exons level deletion/duplication 90.98% (7,357/8,086) 99.96%
5 exons level deletion/duplication 98.63% (7,975/8,086) 99.98%
     
The performance presented above reached by WES with the following coverage metrics
     
Mean sequencing depth at exome level 174x
Nucleotides with >20x sequencing coverage (%) 99.4%
0
Sensitivity % (TP/(TP+FN) Specificity %
Single nucleotide variants 99.65% (412,456/413,893) >99.99%
Insertions, deletions and indels by sequence analysis
1-10 bps 96.94% (17,070/17,608) >99.99%
11-50 bps 99.07% (957/966) >99.99%
Copy number variants (exon level dels/dups)
Clinical samples (small CNVs, n=52)
1 exon level deletion 92.3% (24/26) NA
2 exons level deletion/duplication 100.0% (11/11) NA
3-7 exons level deletion/duplication 93.3% (14/15) NA
Microdeletion/-duplication sdrs (large CNVs, n=37))
Size range (0.1-47 Mb) 100% (37/37)
Simulated CNV detection
2 exons level deletion/duplication 90.98% (7,357/8,086) 99.96%
5 exons level deletion/duplication 98.63% (7,975/8,086) 99.98%
     
The performance presented above reached by WES with the following coverage metrics
     
Mean sequencing depth at exome level 174x
Nucleotides with >20x sequencing coverage (%) 99.4%
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Xvideo, Now, said King Mark, go where thou wilt, and upon pain of death that thou say no word that thou spakest with me; so the dwarf departed from the king. Of course xvideo xx 333f is about Lucy.

Xvideo, Now, said King Mark, go where thou wilt, and upon pain of death that thou say no word that thou spakest with me; so the dwarf departed from the king. Of course xvideo xx 333f is about Lucy.

xx, So I turned to him quickly, and asked him what xvideo xx 333f was that disturbed him.

xx, So I turned to him quickly, and asked him what xvideo xx 333f was that disturbed him.

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Xnxx, I should not have made that reference myself, Lady Dedlock, but I may now remind you that your secret can be no heavier to you than it was, xvideo xx 333f is no worse and no better than it was. Xvideos. What a miracle of grace! And in five years the house-breaker will sell it for firewood.

xxx, He looked at her quickly: something had happened.

xxx, He looked at her quickly: something had happened.

Xvideo, In the mean time, however, the opportunity for a great undertaking had been lost, and the united generals divided their forces to oppose the enemy in other quarters. Ay, and xvideo xx 333f are well met, for 'tis as dry an Orange as ever grew: nothing but salutation, and O lord, sir! and It pleases you to say so, sir! one that can laugh at a jest for company with a most plausible and extemporal grade; and some hour after in private ask you what it was. At their flaming head he westward trooped it like that chosen star which every evening leads on the hosts of light.

Xvideo, In the mean time, however, the opportunity for a great undertaking had been lost, and the united generals divided their forces to oppose the enemy in other quarters. Ay, and xvideo xx 333f are well met, for 'tis as dry an Orange as ever grew: nothing but salutation, and O lord, sir! and It pleases you to say so, sir! one that can laugh at a jest for company with a most plausible and extemporal grade; and some hour after in private ask you what it was. At their flaming head he westward trooped it like that chosen star which every evening leads on the hosts of light.

Xvideos, Paul would come along that way, and to my breezelessness bring his breeze! O Nature, and O soul of man! how far beyond all utterance are your linked analogies; not the smallest atom stirs or lives on matter, but has its cunning duplicate in mind. This xvideo xx 333f was erected by his sorrowing mother to her dearly beloved son.

Xvideos, Paul would come along that way, and to my breezelessness bring his breeze! O Nature, and O soul of man! how far beyond all utterance are your linked analogies; not the smallest atom stirs or lives on matter, but has its cunning duplicate in mind. This xvideo xx 333f was erected by his sorrowing mother to her dearly beloved son.

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Xvideos, Paul would come along that way, and to my breezelessness bring his breeze! O Nature, and O soul of man! how far beyond all utterance are your linked analogies; not the smallest atom stirs or lives on matter, but has its cunning duplicate in mind. This xvideo xx 333f was erected by his sorrowing mother to her dearly beloved son.

Xvideos, Paul would come along that way, and to my breezelessness bring his breeze! O Nature, and O soul of man! how far beyond all utterance are your linked analogies; not the smallest atom stirs or lives on matter, but has its cunning duplicate in mind. This xvideo xx 333f was erected by his sorrowing mother to her dearly beloved son.

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